2. Signaling Pathways
  3. GPCR/G Protein
  4. RXFP Receptor
  5. RXFP Receptor Agonist

RXFP Receptor Agonist

RXFP Receptor Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-P10728
    B7-33
    		Agonist
    B7-33 is a single-chain relaxin mimetic. B7-33 is a selective relaxin receptor 1 (RXFP1) agonist. B7-33 binds to RXFP1 and preferentially activates thepERK pathway over cAMP in cells (with RXFP1 expression). B7-33 is an anti-fibrotic agent. B7-33 has cardioprotective effects.
  • HY-162401
    AZ7976
    		Agonist
    AZ7976 (Compound 42) is a highly selective agonist for the Relaxin Family Peptide Receptor 1 (RXFP1) (pEC50 > 10.5). AZ7976 enhances RXFP1's cAMP signaling through an allosteric mechanism, thereby physiologically increasing heart rate. AZ7976 can be used in the field of cardiovascular disease research.