2. Signaling Pathways
  3. Epigenetics
  4. SF3B1
  5. SF3B1 Inhibitor

SF3B1 Inhibitor

SF3B1 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-16399
    Pladienolide B
    		Inhibitor ≥99.0%
    Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis.
  • HY-111517
    H3B-8800
    		Inhibitor 98.18%
    H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant.