1. Signaling Pathways
  2. Epigenetics
  3. Small Interfering RNA (siRNA)
  4. Small Interfering RNA (siRNA) Inhibitor

Small Interfering RNA (siRNA) Inhibitor

Small Interfering RNA (siRNA) Inhibitors (9):

Cat. No. Product Name Effect Purity
  • HY-147425A
    Zerlasiran sodium
    Inhibitor
    Zerlasiran sodium is an apolipoprotein A (ApoA) synthesis reducer.
  • HY-132590A
    Revusiran sodium
    Inhibitor
    Revusiran sodium is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran sodium can be used for transthyretin (TTR)-mediated amyloidosis research.
  • HY-147266A
    Elebsiran
    Inhibitor
    Elebsiran is a siRNA against hepatitis B and D virus infections .
  • HY-153493A
    PF-04523655 sodium
    Inhibitor
    PF-04523655 sodium is a siRNA directed against RTP801 gene. RTP801 sodium is an inhibitor of the mammalian target of rampamycin complex 1 (mTORC1) and downstream transcription factor HIF-1.
  • HY-153492A
    Olpasiran sodium
    Inhibitor
    Olpasiran sodium is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
  • HY-153483A
    Bamosiran sodium
    Inhibitor
    Bamosiran sodium is a small interfering RNA targeting β-adrenergic receptor 2, and is used to lower intraocular pressure
  • HY-153482A
    ATU027 sodium
    Inhibitor
    ATU027 sodium is a siRNA, which silences expression of protein kinase N3 (PKN3) in the vascular endothelium. ATU027 sodium has previously been shown to inhibit local tumor invasion as well as lymph node and pulmonary metastasis in mouse cancer models.
  • HY-132603A
    AB-729 sodium
    Inhibitor
    AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
  • HY-147278A
    Manusiran sodium
    Inhibitor
    Manusiran (SLN124) sodium, a GalNAc conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6), reduces plasma iron and increases hepcidin levels[1][2].