2. Signaling Pathways
  3. Immunology/Inflammation
  4. Transmembrane Glycoprotein
  5. Transmembrane Glycoprotein Modulator

Transmembrane Glycoprotein Modulator

Transmembrane Glycoprotein Modulators (3):

Cat. No. Product Name Effect Purity
  • HY-128128
    ASN04421891
    		Modulator 99.00%
    ASN04421891 is a potent GPR17 receptor modulator, with an EC50 of 3.67 nM in [35S]GTPγS binding assay. ASN04421891 can be used for neurodegenerative diseases research.
  • HY-164311
    GPR17 modulator-1
    		Modulator
    GPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17, with an IC50<10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable.
  • HY-144399A
    CD33 splicing modulator 1 hydrochloride
    		Modulator
    CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid cell surface receptor known to regulate microglial activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in the cellular mRNA pool and can be used to study neurodegenerative diseases including Alzheimer's disease.