2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. WNK Kinase
  5. WNK Kinase Inhibitor

WNK Kinase Inhibitor

WNK Kinase Isoform Comparison

WNK Kinase Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-100626
    WNK463
    		Inhibitor 99.75%
    WNK463 is an orally bioavailable pan-With-No-Lysine (K) (WNK)-kinase inhibitor with IC50s of 5 nM, 1 nM, 6 nM, and 9 nM for WNK1, WNK2, WNK3, and WNK4, respectively.
  • HY-112094
    WNK-IN-11
    		Inhibitor 99.13%
    WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
  • HY-119727
    WNK-IN-1
    		Inhibitor 98.87%
    WNK-IN-1 (compound 7) is a ATP noncompetitive With-No-Lysine (WNK) kinase inhibitor (IC50=95 nM). WNK-IN-1 can be used to regulate cardiovascular homeostasis.
  • HY-112094S
    WNK-IN-11-d3
    		Inhibitor 99.84%
    WNK-IN-11-d3 is an orally active, selective and potent With-No-Lysine (WNK) kinase inhibitor. WNK-IN-11-d3 is effective at regulating cardiovascular homeostasis[1].