Trifluralin

Cat. No.: HY-B2050 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Trifluralin is a commonly used pre-emergence herbicide.

For research use only. We do not sell to patients.

Trifluralin Chemical Structure

CAS No. : 1582-09-8

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

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Other Forms of Trifluralin:

Trifluralin-d₁₄ Get quote
Trifluralin (Standard) Get quote

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Biological Activity
Purity & Documentation
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Description

Trifluralin is a commonly used pre-emergence herbicide. Trifluralin is generally applied to the soil to provide control of a variety of annual grass and broadleaf weed species. It inhibits root development by interrupting mitosis, and thus can control weeds as they germinate.

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-8	IC₅₀	750 nM Compound: 1	Antimicrobial activity against Cryptosporidium parvum infected in HCT8 cells assessed as parasite count after 72 to 120 hrs Antimicrobial activity against Cryptosporidium parvum infected in HCT8 cells assessed as parasite count after 72 to 120 hrs	[PMID: 21889338]
HFF	IC₅₀	0.52 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	1.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	1.9 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	13.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	2.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	23.3 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	23.4 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	27 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	4.1 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	4.2 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	5.1 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	5.3 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay	[PMID: 20145086]
THP-1	CC₅₀	> 50 μM Compound: TFL	Cytotoxicity against human THP1 cells after 48 hrs by propidium iodide and SYBR14 satining-base flow cytometry Cytotoxicity against human THP1 cells after 48 hrs by propidium iodide and SYBR14 satining-base flow cytometry	[PMID: 19926293]
THP-1	IC₅₀	> 50 μM Compound: TFL	Antileishmanial activity against Leishmania infantum A1 amastigotes infected in human THP1 cells assessed as reduction in intracellular parasite load after 48 hrs by Giemsa staining Antileishmanial activity against Leishmania infantum A1 amastigotes infected in human THP1 cells assessed as reduction in intracellular parasite load after 48 hrs by Giemsa staining	[PMID: 19926293]

Molecular Weight

335.28

Formula

C₁₃H₁₆F₃N₃O₄

CAS No.

1582-09-8

Appearance

Solid

Color

Pink to red

SMILES

FC(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (298.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9826 mL	14.9129 mL	29.8258 mL
5 mM	0.5965 mL	2.9826 mL	5.9652 mL
10 mM	0.2983 mL	1.4913 mL	2.9826 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (244 KB) SDS (728 KB)

COA (251 KB) HNMR (280 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9826 mL	14.9129 mL	29.8258 mL	74.5645 mL
	5 mM	0.5965 mL	2.9826 mL	5.9652 mL	14.9129 mL
	10 mM	0.2983 mL	1.4913 mL	2.9826 mL	7.4565 mL
	15 mM	0.1988 mL	0.9942 mL	1.9884 mL	4.9710 mL
	20 mM	0.1491 mL	0.7456 mL	1.4913 mL	3.7282 mL
	25 mM	0.1193 mL	0.5965 mL	1.1930 mL	2.9826 mL
	30 mM	0.0994 mL	0.4971 mL	0.9942 mL	2.4855 mL
	40 mM	0.0746 mL	0.3728 mL	0.7456 mL	1.8641 mL
	50 mM	0.0597 mL	0.2983 mL	0.5965 mL	1.4913 mL
	60 mM	0.0497 mL	0.2485 mL	0.4971 mL	1.2427 mL
	80 mM	0.0373 mL	0.1864 mL	0.3728 mL	0.9321 mL
	100 mM	0.0298 mL	0.1491 mL	0.2983 mL	0.7456 mL

Trifluralin Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trifluralin1582-09-8OthersInhibitorinhibitorinhibit

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