2. Anti-infection
  3. HBV
  4. AB-836

AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein.

For research use only. We do not sell to patients.

AB-836 Chemical Structure

AB-836 Chemical Structure

CAS No. : 2445597-31-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 550 In-stock
Solution
10 mM * 1 mL in DMSO USD 550 In-stock
Solid
5 mg USD 500 In-stock
10 mg USD 850 In-stock
25 mg USD 1800 In-stock
50 mg USD 3000 In-stock
100 mg USD 4600 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

AB-836 Related Antibodies

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Description

AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein[1].

Molecular Weight

400.35

Formula

C20H15F3N4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC1=C(C#N)C=C(NC(N(C)[C@H](C)C2=CNC(C3=C2C=C(F)C(F)=C3)=O)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (249.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4978 mL 12.4891 mL 24.9781 mL
5 mM 0.4996 mL 2.4978 mL 4.9956 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4978 mL 12.4891 mL 24.9781 mL 62.4454 mL
5 mM 0.4996 mL 2.4978 mL 4.9956 mL 12.4891 mL
10 mM 0.2498 mL 1.2489 mL 2.4978 mL 6.2445 mL
15 mM 0.1665 mL 0.8326 mL 1.6652 mL 4.1630 mL
20 mM 0.1249 mL 0.6245 mL 1.2489 mL 3.1223 mL
25 mM 0.0999 mL 0.4996 mL 0.9991 mL 2.4978 mL
30 mM 0.0833 mL 0.4163 mL 0.8326 mL 2.0815 mL
40 mM 0.0624 mL 0.3122 mL 0.6245 mL 1.5611 mL
50 mM 0.0500 mL 0.2498 mL 0.4996 mL 1.2489 mL
60 mM 0.0416 mL 0.2082 mL 0.4163 mL 1.0408 mL
80 mM 0.0312 mL 0.1561 mL 0.3122 mL 0.7806 mL
100 mM 0.0250 mL 0.1249 mL 0.2498 mL 0.6245 mL
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AB-836 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AB-8362445597-31-7AB836AB 836HBVHepatitis B viruscapsidoralreplicationcore proteinInhibitorinhibitorinhibit

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