1. Cell Cycle/DNA Damage Stem Cell/Wnt
  2. Casein Kinase
  3. Ac-VDVAD-CHO TFA

Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC50: 46 and 15 nM).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-VDVAD-CHO TFA Chemical Structure

Ac-VDVAD-CHO TFA Chemical Structure

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Description

Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1].

Molecular Weight

657.59

Formula

C25H38F3N5O12

Appearance

Solid

Sequence

Ac-Val-Asp-Val-Ala-Asp-CHO

Sequence Shortening

Ac-VDVAD-CHO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (152.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5207 mL 7.6035 mL 15.2070 mL
5 mM 0.3041 mL 1.5207 mL 3.0414 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5207 mL 7.6035 mL 15.2070 mL 38.0176 mL
5 mM 0.3041 mL 1.5207 mL 3.0414 mL 7.6035 mL
10 mM 0.1521 mL 0.7604 mL 1.5207 mL 3.8018 mL
15 mM 0.1014 mL 0.5069 mL 1.0138 mL 2.5345 mL
20 mM 0.0760 mL 0.3802 mL 0.7604 mL 1.9009 mL
25 mM 0.0608 mL 0.3041 mL 0.6083 mL 1.5207 mL
30 mM 0.0507 mL 0.2535 mL 0.5069 mL 1.2673 mL
40 mM 0.0380 mL 0.1901 mL 0.3802 mL 0.9504 mL
50 mM 0.0304 mL 0.1521 mL 0.3041 mL 0.7604 mL
60 mM 0.0253 mL 0.1267 mL 0.2535 mL 0.6336 mL
80 mM 0.0190 mL 0.0950 mL 0.1901 mL 0.4752 mL
100 mM 0.0152 mL 0.0760 mL 0.1521 mL 0.3802 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ac-VDVAD-CHO TFA
Cat. No.:
HY-134567A
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