Ac-VRPR-AMC TFA

Cat. No.: HY-P4449A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Ac-VRPR-AMC TFA is a fluorogenic metacaspase substrate. Ac-VRPR-AMC TFA can be used to assay metacaspase activity.

For research use only. We do not sell to patients.

Ac-VRPR-AMC TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 155	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Ac-VRPR-AMC TFA:

Ac-VRPR-AMC Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Ac-VRPR-AMC TFA is a fluorogenic metacaspase substrate. Ac-VRPR-AMC TFA can be used to assay metacaspase activity^[1].

Molecular Weight

953.88

Formula

C₃₈H₅₃F₆N₁₁O₁₁

Appearance

Solid

Sequence

Ac-Val-Arg-Pro-{Arg-AMC}

Sequence Shortening

Ac-VRP-{Arg-AMC}

SMILES

CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O)=O)C=C1O3)=CC3=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (104.83 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0483 mL	5.2417 mL	10.4835 mL
5 mM	0.2097 mL	1.0483 mL	2.0967 mL
10 mM	0.1048 mL	0.5242 mL	1.0483 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Spungin, et al. "Assessment of metacaspase activity in phytoplankton." Bio-protocol 9.16 (2019): e3341-e3341. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.0483 mL	5.2417 mL	10.4835 mL	26.2087 mL
	5 mM	0.2097 mL	1.0483 mL	2.0967 mL	5.2417 mL
	10 mM	0.1048 mL	0.5242 mL	1.0483 mL	2.6209 mL
	15 mM	0.0699 mL	0.3494 mL	0.6989 mL	1.7472 mL
	20 mM	0.0524 mL	0.2621 mL	0.5242 mL	1.3104 mL
	25 mM	0.0419 mL	0.2097 mL	0.4193 mL	1.0483 mL
	30 mM	0.0349 mL	0.1747 mL	0.3494 mL	0.8736 mL
	40 mM	0.0262 mL	0.1310 mL	0.2621 mL	0.6552 mL
	50 mM	0.0210 mL	0.1048 mL	0.2097 mL	0.5242 mL
	60 mM	0.0175 mL	0.0874 mL	0.1747 mL	0.4368 mL
	80 mM	0.0131 mL	0.0655 mL	0.1310 mL	0.3276 mL
	100 mM	0.0105 mL	0.0524 mL	0.1048 mL	0.2621 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Ac-VRPR-AMC TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-VRPR-AMCCaspaseFluorescent substrateactivity testInhibitorinhibitorinhibit

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