1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage Apoptosis
  2. β-glucuronidase DNA/RNA Synthesis Apoptosis
  3. Aceglatone

Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells.

For research use only. We do not sell to patients.

Aceglatone Chemical Structure

Aceglatone Chemical Structure

CAS No. : 642-83-1

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Description

Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1].

Molecular Weight

258.18

Formula

C10H10O8

CAS No.
SMILES

CC(O[C@H]1[C@]2([H])[C@@](OC1=O)([H])[C@H](C(O2)=O)OC(C)=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Aceglatone
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HY-119621
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