1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Acetophenazine

Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression.

For research use only. We do not sell to patients.

Acetophenazine Chemical Structure

Acetophenazine Chemical Structure

CAS No. : 2751-68-0

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Based on 1 publication(s) in Google Scholar

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Description

Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

IC50 & Target[1]

D2 Receptor

 

In Vivo

Acetophenazine (2.4 mg/kg; i.h.; single dosage) significantly prolongs the time lapse from the first fight to submission and the actual fighting time to submission in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL mice (10-12 weeks)[3]
Dosage: 2.4 mg/kg
Administration: i.h.; single dosage
Result: Significantly prolonged the time lapse from the first fight to submission and the actual fighting time to submission.
Molecular Weight

411.56

Formula

C23H29N3O2S

CAS No.
SMILES

CC(C1=CC=C(SC2=C3C=CC=C2)C(N3CCCN4CCN(CC4)CCO)=C1)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Acetophenazine
Cat. No.:
HY-116916
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