2. Neuronal Signaling
  3. Cholinesterase (ChE) Monoamine Oxidase
  4. AChE/BChE/MAO-B-IN-5

AChE/BChE/MAO-B-IN-5 is a multitarget inhibitor of cholinesterases (AChE and BChE) and monoamine oxidase MAO-B with blood–brain barrier permeability. It exhibits IC50 values of 0.24 µM, 6.29 µM, and 0.11 µM against AChE, BChE, and MAO-B, respectively. AChE/BChE/MAO-B-IN-5 shows promise for research in the field of neurodegenerative diseases such as Alzheimer's disease.

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AChE/BChE/MAO-B-IN-5 Chemical Structure

AChE/BChE/MAO-B-IN-5 Chemical Structure

CAS No. : 1432738-00-5

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AChE/BChE/MAO-B-IN-5 Related Antibodies

Top Publications Citing Use of Products

View All Cholinesterase (ChE) Isoform Specific Products:

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AChE BChE

View All Monoamine Oxidase Isoform Specific Products:

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MAO-A MAO-B

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Description

AChE/BChE/MAO-B-IN-5 is a multitarget inhibitor of cholinesterases (AChE and BChE) and monoamine oxidase MAO-B with blood–brain barrier permeability. It exhibits IC50 values of 0.24 µM, 6.29 µM, and 0.11 µM against AChE, BChE, and MAO-B, respectively. AChE/BChE/MAO-B-IN-5 shows promise for research in the field of neurodegenerative diseases such as Alzheimer's disease[1].

IC50 & Target

MAO-B

0.11 μM (IC50)

AChE

0.24 μM (IC50)

BChE

6.29 μM (IC50)

Molecular Weight

381.35

Formula

C22H14F3NO2
CAS No.
SMILES

O=C1N(CC2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)C(C4=C1C=CC=C4)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AChE/BChE/MAO-B-IN-5 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/BChE/MAO-B-IN-51432738-00-5Cholinesterase (ChE)Monoamine OxidaseMAOInhibitorinhibitorinhibit

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