2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. ACT-672125

ACT-672125 is a potent CXCR3 antagonist with IC50 value of 239 nM in human blood. ACT-672125 has activity for hERG with IC50 value of 18μM. ACT-672125 can be used for the research of autoimmune diseases.

For research use only. We do not sell to patients.

ACT-672125 Chemical Structure

ACT-672125 Chemical Structure

CAS No. : 1449367-94-5

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ACT-672125 Related Antibodies

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Description

ACT-672125 is a potent CXCR3 antagonist with IC50 value of 239 nM in human blood. ACT-672125 has activity for hERG with IC50 value of 18μM. ACT-672125 can be used for the research of autoimmune diseases[1].

IC50 & Target

IC50: 239 nM (CXCR3); 18 μM (hERG)[1].
Molecular Weight

586.59

Formula

C25H25F3N10O2S
CAS No.
SMILES

FC(F)(C1=NC(C2=NC3=CC=C(C4=NOC(C)=N4)C=C3N2)=C(N5C[C@H](N(CC5)C(CN6C(C)=NC(C)=N6)=O)C)S1)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ACT-672125 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACT-6721251449367-94-5ACT672125ACT 672125CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsCXCR3autoimmune diseasesInhibitorinhibitorinhibit

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