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  4. Activated DPG Subunit

Activated DPG Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy.

For research use only. We do not sell to patients.

Activated DPG Subunit Chemical Structure

Activated DPG Subunit Chemical Structure

CAS No. : 1155309-89-9

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Description

Activated DPG Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

Molecular Weight

942.44

Formula

C51H53ClN7O7P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(Cl)(N(C)C)OC[C@H](CN(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4)O[C@H]4N5C=NC6=C5N=C(NC(CC7=CC=CC=C7)=O)N=C6OCC(C=C8)=CC=C8OC(C(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5.71 mg/mL (6.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0611 mL 5.3054 mL 10.6108 mL
5 mM 0.2122 mL 1.0611 mL 2.1222 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0611 mL 5.3054 mL 10.6108 mL 26.5269 mL
5 mM 0.2122 mL 1.0611 mL 2.1222 mL 5.3054 mL
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Activated DPG Subunit Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Activated DPG Subunit1155309-89-9OthersInhibitorinhibitorinhibit

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