2. GPCR/G Protein
  3. Formyl Peptide Receptor (FPR)
  4. AG-09/1

AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense.

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AG-09/1 Chemical Structure

AG-09/1 Chemical Structure

CAS No. : 356776-32-4

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Based on 1 publication(s) in Google Scholar

AG-09/1 Related Antibodies

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Description

AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense[1].

IC50 & Target

FPR1[1]
In Vitro

N-formyl peptides activate phagocytes through G protein-coupled receptors known as FPR. FPR1 was the first FPR cloned and encodes a high-affinity receptor for fMLF[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AG-09/1 Related Antibodies
Molecular Weight

358.37

Formula

C16H14N4O4S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC1=CC=C([N+]([O-])=O)C=C1)CSC2=NC3=CC=C(OC)C=C3N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (697.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7904 mL 13.9521 mL 27.9041 mL
5 mM 0.5581 mL 2.7904 mL 5.5808 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7904 mL 13.9521 mL 27.9041 mL 69.7603 mL
5 mM 0.5581 mL 2.7904 mL 5.5808 mL 13.9521 mL
10 mM 0.2790 mL 1.3952 mL 2.7904 mL 6.9760 mL
15 mM 0.1860 mL 0.9301 mL 1.8603 mL 4.6507 mL
20 mM 0.1395 mL 0.6976 mL 1.3952 mL 3.4880 mL
25 mM 0.1116 mL 0.5581 mL 1.1162 mL 2.7904 mL
30 mM 0.0930 mL 0.4651 mL 0.9301 mL 2.3253 mL
40 mM 0.0698 mL 0.3488 mL 0.6976 mL 1.7440 mL
50 mM 0.0558 mL 0.2790 mL 0.5581 mL 1.3952 mL
60 mM 0.0465 mL 0.2325 mL 0.4651 mL 1.1627 mL
80 mM 0.0349 mL 0.1744 mL 0.3488 mL 0.8720 mL
100 mM 0.0279 mL 0.1395 mL 0.2790 mL 0.6976 mL
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AG-09/1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AG-09/1356776-32-4Formyl Peptide Receptor (FPR)formylpeptidereceptorFPR1hostdefenseInhibitorinhibitorinhibit

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