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  4. AGA-(C8R) HNG17, humanin derivative TFA

AGA-(C8R) HNG17, humanin derivative TFA 

Cat. No.: HY-P1851A Purity: 98.34%
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AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

AGA-(C8R) HNG17, humanin derivative TFA Chemical Structure

AGA-(C8R) HNG17, humanin derivative TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 250 In-stock
10 mg USD 420 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of AGA-(C8R) HNG17, humanin derivative TFA:

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Description

AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults[1].

Molecular Weight

1850.04

Formula

C80H135F3N20O26

Appearance

Solid

Color

White to off-white

Sequence

Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro

Sequence Shortening

PAGASRLLLLTGEIDLP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (54.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 20 mg/mL (10.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5405 mL 2.7026 mL 5.4053 mL
5 mM 0.1081 mL 0.5405 mL 1.0811 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.5405 mL 2.7026 mL 5.4053 mL 13.5132 mL
5 mM 0.1081 mL 0.5405 mL 1.0811 mL 2.7026 mL
10 mM 0.0541 mL 0.2703 mL 0.5405 mL 1.3513 mL
DMSO 15 mM 0.0360 mL 0.1802 mL 0.3604 mL 0.9009 mL
20 mM 0.0270 mL 0.1351 mL 0.2703 mL 0.6757 mL
25 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.5405 mL
30 mM 0.0180 mL 0.0901 mL 0.1802 mL 0.4504 mL
40 mM 0.0135 mL 0.0676 mL 0.1351 mL 0.3378 mL
50 mM 0.0108 mL 0.0541 mL 0.1081 mL 0.2703 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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AGA-(C8R) HNG17, humanin derivative TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AGA-(C8R) HNG17, humanin derivative TFA
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