2. Neuronal Signaling
  3. Imidazoline Receptor
  4. AGN 192403 hydrochloride

AGN 192403 hydrochloride  (Synonyms: BRD4780 hydrochloride)

Cat. No.: HY-101374A Purity: ≥99.0%
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AGN 192403 (BRD4780) hydrochloride is an I1-Imidazoline receptor antagonist for cardiovascular and neurological research.

For research use only. We do not sell to patients.

AGN 192403 hydrochloride Chemical Structure

AGN 192403 hydrochloride Chemical Structure

CAS No. : 1021868-90-5

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AGN 192403 hydrochloride Related Antibodies

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Description

AGN 192403 (BRD4780) hydrochloride is an I1-Imidazoline receptor antagonist for cardiovascular and neurological research[1].

Molecular Weight

189.73

Formula

C10H20ClN
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)[C@@H]1[C@@H](N)[C@H]2CC[C@@H]1C2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 19 mg/mL (100.14 mM; Need ultrasonic and warming)

DMSO : 19 mg/mL (100.14 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2706 mL 26.3532 mL 52.7065 mL
5 mM 1.0541 mL 5.2706 mL 10.5413 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 5.2706 mL 26.3532 mL 52.7065 mL 131.7662 mL
5 mM 1.0541 mL 5.2706 mL 10.5413 mL 26.3532 mL
10 mM 0.5271 mL 2.6353 mL 5.2706 mL 13.1766 mL
15 mM 0.3514 mL 1.7569 mL 3.5138 mL 8.7844 mL
20 mM 0.2635 mL 1.3177 mL 2.6353 mL 6.5883 mL
25 mM 0.2108 mL 1.0541 mL 2.1083 mL 5.2706 mL
30 mM 0.1757 mL 0.8784 mL 1.7569 mL 4.3922 mL
40 mM 0.1318 mL 0.6588 mL 1.3177 mL 3.2942 mL
50 mM 0.1054 mL 0.5271 mL 1.0541 mL 2.6353 mL
60 mM 0.0878 mL 0.4392 mL 0.8784 mL 2.1961 mL
80 mM 0.0659 mL 0.3294 mL 0.6588 mL 1.6471 mL
100 mM 0.0527 mL 0.2635 mL 0.5271 mL 1.3177 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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AGN 192403 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AGN 1924031021868-90-5BRD4780AGN192403AGN-192403BRD 4780BRD-4780Imidazoline ReceptorcardiovascularHeart rateneurologicalAGN-192403 hydrochlorideAGN192403 hydrochlorideInhibitorinhibitorinhibit

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