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  4. AIE-ER

AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum.

For research use only. We do not sell to patients.

AIE-ER Chemical Structure

AIE-ER Chemical Structure

CAS No. : 2653341-17-2

Size Price Stock Quantity
5 mg USD 189 In-stock
10 mg USD 315 In-stock
25 mg USD 660 In-stock
50 mg USD 1056 In-stock
100 mg USD 1690 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

AIE-ER Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum[1].

In Vitro

AIE-ER (1-10 μM; 24 h) exhibits low cytotoxicity in HeLa cells, maintaining good cell viability (> 75%) even at a concentration of 10 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AIE-ER Related Antibodies
Molecular Weight

652.80

Formula

C40H36N4O3S
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

N#C/C(C1=CC=C(C2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)C=C1)=C\C4=CC=C(N(C5=CC=CC=C5)C6=CC=CC=C6)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (153.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5319 mL 7.6593 mL 15.3186 mL
5 mM 0.3064 mL 1.5319 mL 3.0637 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5319 mL 7.6593 mL 15.3186 mL 38.2966 mL
5 mM 0.3064 mL 1.5319 mL 3.0637 mL 7.6593 mL
10 mM 0.1532 mL 0.7659 mL 1.5319 mL 3.8297 mL
15 mM 0.1021 mL 0.5106 mL 1.0212 mL 2.5531 mL
20 mM 0.0766 mL 0.3830 mL 0.7659 mL 1.9148 mL
25 mM 0.0613 mL 0.3064 mL 0.6127 mL 1.5319 mL
30 mM 0.0511 mL 0.2553 mL 0.5106 mL 1.2766 mL
40 mM 0.0383 mL 0.1915 mL 0.3830 mL 0.9574 mL
50 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7659 mL
60 mM 0.0255 mL 0.1277 mL 0.2553 mL 0.6383 mL
80 mM 0.0191 mL 0.0957 mL 0.1915 mL 0.4787 mL
100 mM 0.0153 mL 0.0766 mL 0.1532 mL 0.3830 mL
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AIE-ER Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AIE-ER2653341-17-2Fluorescent DyeAIEEndoplasmic ReticulumInhibitorinhibitorinhibit

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