1. Cell Cycle/DNA Damage
  2. DNA Alkylator/Crosslinker
  3. Alagebrium bromide

Alagebrium bromide  (Synonyms: ALT711 bromide)

Cat. No.: HY-106024A
Handling Instructions

Alagebrium bromide is an analog of Alagebrium Chloride (HY-106024B), a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF).

For research use only. We do not sell to patients.

Alagebrium bromide Chemical Structure

Alagebrium bromide Chemical Structure

CAS No. : 181069-80-7

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Other In-stock Forms of Alagebrium bromide:

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Top Publications Citing Use of Products

1 Publications Citing Use of MCE Alagebrium bromide

WB

    Alagebrium bromide purchased from MedChemExpress. Usage Cited in: Am J Transl Res. 2019 Mar 15;11(3):1569-1580.  [Abstract]

    Western blotting analysis of TSP-1 protein expression, and results show that TSP-1 expression in HUVECs treated with ALT-711 under CML-BSA condition is enhanced by miR-27b inhibitor.
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    Description

    Alagebrium bromide is an analog of Alagebrium Chloride (HY-106024B), a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF)[1].

    Molecular Weight

    312.23

    Formula

    C13H14BrNOS

    CAS No.
    SMILES

    O=C(C1=CC=CC=C1)C[N+]2=CSC(C)=C2C.[Br-]

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

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    Alagebrium bromide Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Alagebrium bromide
    Cat. No.:
    HY-106024A
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