1. Anti-infection
  2. Bacterial Antibiotic
  3. Alamethicin

Alamethicin, isolated from Trichoderma viride, is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Alamethicin Chemical Structure

Alamethicin Chemical Structure

CAS No. : 27061-78-5

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1 mg USD 120 In-stock
5 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Alamethicin, isolated from Trichoderma viride, is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes[1][2].

Molecular Weight

1964.34

Formula

C92H150N22O25

CAS No.
Appearance

Solid

Color

White to yellow

Sequence

Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phl

Structure Classification
Initial Source

fungus Trichoderma viride

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (50.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5091 mL 2.5454 mL 5.0908 mL
5 mM 0.1018 mL 0.5091 mL 1.0182 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5091 mL 2.5454 mL 5.0908 mL 12.7269 mL
5 mM 0.1018 mL 0.5091 mL 1.0182 mL 2.5454 mL
10 mM 0.0509 mL 0.2545 mL 0.5091 mL 1.2727 mL
15 mM 0.0339 mL 0.1697 mL 0.3394 mL 0.8485 mL
20 mM 0.0255 mL 0.1273 mL 0.2545 mL 0.6363 mL
25 mM 0.0204 mL 0.1018 mL 0.2036 mL 0.5091 mL
30 mM 0.0170 mL 0.0848 mL 0.1697 mL 0.4242 mL
40 mM 0.0127 mL 0.0636 mL 0.1273 mL 0.3182 mL
50 mM 0.0102 mL 0.0509 mL 0.1018 mL 0.2545 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Alamethicin
Cat. No.:
HY-N6708
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