2. Protein Tyrosine Kinase/RTK Cell Cycle/DNA Damage
  3. Anaplastic lymphoma kinase (ALK) CDK FAK
  4. ALK-IN-29

ALK-IN-29 (compound 4c) has a certain inhibitory effect on tyrosine protein kinases ALK, CDK2/CyclinE1 and FAK, among which the strongest inhibitory effect on ALK kinase is 40.63% at a concentration of 10 μM. ALK-IN-29 can be used for anti-cancer research.

For research use only. We do not sell to patients.

ALK-IN-29 Chemical Structure

ALK-IN-29 Chemical Structure

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ALK-IN-29 Related Antibodies

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

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Description

ALK-IN-29 (compound 4c) has a certain inhibitory effect on tyrosine protein kinases ALK, CDK2/CyclinE1 and FAK, among which the strongest inhibitory effect on ALK kinase is 40.63% at a concentration of 10 μM. ALK-IN-29 can be used for anti-cancer research[1].

IC50 & Target

CDK2

 

Molecular Weight

457.58

Formula

C29H32FN3O
SMILES

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC(C4=N5)=C(C6=CC=C(F)C=C6)N7C5=CC=N7
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ALK-IN-29 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALK-IN-29Anaplastic lymphoma kinase (ALK)CDKFAKAnaplastic lymphoma kinaseALK tyrosine kinase receptorCD246Cluster of differentiation 246Cyclin dependent kinasePTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseInhibitorinhibitorinhibit

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ALK-IN-29
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HY-168513
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