2. Cytoskeleton
  3. Integrin
  4. α2β1 Integrin Ligand Peptide TFA

α2β1 Integrin Ligand Peptide TFA  (Synonyms: DGEA peptide TFA)

Cat. No.: HY-P1868A Purity: 99.02%
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α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

α2β1 Integrin Ligand Peptide TFA Chemical Structure

α2β1 Integrin Ligand Peptide TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 120 In-stock
5 mg USD 350 In-stock
10 mg USD 550 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 2 publication(s) in Google Scholar

Other Forms of α2β1 Integrin Ligand Peptide TFA:

α2β1 Integrin Ligand Peptide TFA Related Antibodies

Top Publications Citing Use of Products

View All Integrin Isoform Specific Products:

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1].

In Vitro

α2β1 Integrin Ligand Peptide (DGEA) TFA (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity[1].
? α2β1 Integrin Ligand PeptideTFA induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM[1].
? α2β1 Integrin Ligand Peptide TFA loses its ability to inhibit SA11 binding at 1.0 mM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

α2β1 Integrin Ligand Peptide TFA Related Antibodies
Molecular Weight

504.37

Formula

C16H23F3N4O11
Appearance

Solid

Color

White to off-white

Sequence

Asp-Gly-Glu-Ala
Sequence Shortening

DGEA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (66.08 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9827 mL 9.9134 mL 19.8267 mL
5 mM 0.3965 mL 1.9827 mL 3.9653 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 20 mg/mL (39.65 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.9827 mL 9.9134 mL 19.8267 mL 49.5668 mL
5 mM 0.3965 mL 1.9827 mL 3.9653 mL 9.9134 mL
10 mM 0.1983 mL 0.9913 mL 1.9827 mL 4.9567 mL
15 mM 0.1322 mL 0.6609 mL 1.3218 mL 3.3045 mL
20 mM 0.0991 mL 0.4957 mL 0.9913 mL 2.4783 mL
25 mM 0.0793 mL 0.3965 mL 0.7931 mL 1.9827 mL
30 mM 0.0661 mL 0.3304 mL 0.6609 mL 1.6522 mL
40 mM 0.0496 mL 0.2478 mL 0.4957 mL 1.2392 mL
50 mM 0.0397 mL 0.1983 mL 0.3965 mL 0.9913 mL
60 mM 0.0330 mL 0.1652 mL 0.3304 mL 0.8261 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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α2β1 Integrin Ligand Peptide TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α2β1 Integrin Ligand PeptideDGEA peptideIntegrinCollagenReceptorInhibitorinhibitorinhibit

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