2. Cytoskeleton
  3. Integrin
  4. α2β1 Integrin Ligand Peptide

α2β1 Integrin Ligand Peptide  (Synonyms: DGEA peptide)

Cat. No.: HY-P1868 Purity: 98.92%
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α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

α2β1 Integrin Ligand Peptide Chemical Structure

α2β1 Integrin Ligand Peptide Chemical Structure

CAS No. : 134580-64-6

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of α2β1 Integrin Ligand Peptide:

α2β1 Integrin Ligand Peptide Related Antibodies

Top Publications Citing Use of Products

View All Integrin Isoform Specific Products:

View All Isoforms
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1].

In Vitro

α2β1 Integrin Ligand Peptide (DGEA) (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity[1].
α2β1 Integrin Ligand Peptide induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM[1].
α2β1 Integrin Ligand Peptide loses its ability to inhibit SA11 binding at 1.0 mM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

α2β1 Integrin Ligand Peptide Related Antibodies
Molecular Weight

390.35

Formula

C14H22N4O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Gly-Glu-Ala
Sequence Shortening

DGEA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (256.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5618 mL 12.8090 mL 25.6180 mL
5 mM 0.5124 mL 2.5618 mL 5.1236 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5618 mL 12.8090 mL 25.6180 mL 64.0451 mL
5 mM 0.5124 mL 2.5618 mL 5.1236 mL 12.8090 mL
10 mM 0.2562 mL 1.2809 mL 2.5618 mL 6.4045 mL
15 mM 0.1708 mL 0.8539 mL 1.7079 mL 4.2697 mL
20 mM 0.1281 mL 0.6405 mL 1.2809 mL 3.2023 mL
25 mM 0.1025 mL 0.5124 mL 1.0247 mL 2.5618 mL
30 mM 0.0854 mL 0.4270 mL 0.8539 mL 2.1348 mL
40 mM 0.0640 mL 0.3202 mL 0.6405 mL 1.6011 mL
50 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.2809 mL
60 mM 0.0427 mL 0.2135 mL 0.4270 mL 1.0674 mL
80 mM 0.0320 mL 0.1601 mL 0.3202 mL 0.8006 mL
100 mM 0.0256 mL 0.1281 mL 0.2562 mL 0.6405 mL
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α2β1 Integrin Ligand Peptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α2β1 Integrin Ligand Peptide134580-64-6DGEA peptideIntegrinInhibitorinhibitorinhibit

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