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alpha-CEHC is a water-soluble metabolite of alpha-tocopherol (α-TOH) with potential antioxidant activity. alpha-CEHC slightly inhibits macrophage-induced low-density lipoprotein (LDL) oxidation, and its inhibitory potency is concentration-dependent.

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alpha-CEHC Chemical Structure

alpha-CEHC Chemical Structure

CAS No. : 4072-32-6

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Based on 1 publication(s) in Google Scholar

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Description

alpha-CEHC is a water-soluble metabolite of alpha-tocopherol (α-TOH) with potential antioxidant activity. alpha-CEHC slightly inhibits macrophage-induced low-density lipoprotein (LDL) oxidation, and its inhibitory potency is concentration-dependent[1][2].

Molecular Weight

278.34

Formula

C16H22O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (71.85 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5927 mL 17.9636 mL 35.9273 mL
5 mM 0.7185 mL 3.5927 mL 7.1855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.30%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5927 mL 17.9636 mL 35.9273 mL 89.8182 mL
5 mM 0.7185 mL 3.5927 mL 7.1855 mL 17.9636 mL
10 mM 0.3593 mL 1.7964 mL 3.5927 mL 8.9818 mL
15 mM 0.2395 mL 1.1976 mL 2.3952 mL 5.9879 mL
20 mM 0.1796 mL 0.8982 mL 1.7964 mL 4.4909 mL
25 mM 0.1437 mL 0.7185 mL 1.4371 mL 3.5927 mL
30 mM 0.1198 mL 0.5988 mL 1.1976 mL 2.9939 mL
40 mM 0.0898 mL 0.4491 mL 0.8982 mL 2.2455 mL
50 mM 0.0719 mL 0.3593 mL 0.7185 mL 1.7964 mL
60 mM 0.0599 mL 0.2994 mL 0.5988 mL 1.4970 mL
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alpha-CEHC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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alpha-CEHC
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HY-113269
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