Amdoxovir (Synonyms: DAPD)

Cat. No.: HY-106155: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Amdoxovir (DAPD) is an orally active nucleoside reverse transcriptase inhibitor. Amdoxovir is active against wild-type and NRTl-resistant viruses. Amdoxovir is the prodrug of dioxolane guanosine. Amdoxovir can be used for research of HIV/AIDS.

For research use only. We do not sell to patients.

Amdoxovir Chemical Structure

CAS No. : 145514-04-1

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All HIV Isoform Specific Products:

View All Isoforms

HIV HIV-1 HIV-2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	CC₅₀	> 100 μM Compound: DAPD, AMDX	Cytotoxicity against human CEM cells after 2 to 4 days by MTT assay Cytotoxicity against human CEM cells after 2 to 4 days by MTT assay	[PMID: 24015326]
HepG2	CC₅₀	> 100 μM Compound: DAPD, AMDX	Cytotoxicity against human HepG2 cells after 2 to 4 days by neutral red dye uptake assay Cytotoxicity against human HepG2 cells after 2 to 4 days by neutral red dye uptake assay	[PMID: 24015326]
Huh-7	CC₅₀	> 100 μM Compound: DAPD, AMDX	Cytotoxicity against human HuH7 cells after 2 to 4 days by MTT assay Cytotoxicity against human HuH7 cells after 2 to 4 days by MTT assay	[PMID: 24015326]
PBMC	CC₅₀	> 100 μM Compound: DAPD, AMDX	Cytotoxicity against human PBMC after 2 to 4 days by MTT assay Cytotoxicity against human PBMC after 2 to 4 days by MTT assay	[PMID: 24015326]
Vero	CC₅₀	> 100 μM Compound: DAPD, AMDX	Cytotoxicity against African green monkey Vero cells after 2 to 4 days by MTT assay Cytotoxicity against African green monkey Vero cells after 2 to 4 days by MTT assay	[PMID: 24015326]

Molecular Weight

252.23

Formula

C₉H₁₂N₆O₃

CAS No.

145514-04-1

SMILES

NC1=C2C(N([C@@H]3O[C@@H](OC3)CO)C=N2)=NC(N)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gripshover BM, et al. Amdoxovir versus placebo with enfuvirtide plus optimized background therapy for HIV-1-infected subjects failing current therapy (AACTG A5118). Antivir Ther. 2006;11(5):619-23. [Content Brief]

Amdoxovir Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amdoxovir145514-04-1DAPDHIVReverse TranscriptaseHuman immunodeficiency virusInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks