2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. AMG 517 (Standard)

AMG 517 (Standard) is the analytical standard of AMG 517. This product is intended for research and analytical applications. AMG 517 is a potent and selective vanilloid receptor-1 (TRPV1) antagonist with an IC50 of 0.5 nM.

For research use only. We do not sell to patients.

AMG 517 (Standard) Chemical Structure

AMG 517 (Standard) Chemical Structure

CAS No. : 659730-32-2

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Description
Molecular Weight

430.40

Formula

C20H13F3N4O2S
CAS No.
SMILES

CC(NC1=NC2=C(OC3=NC=NC(C4=CC=C(C(F)(F)F)C=C4)=C3)C=CC=C2S1)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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AMG 517 (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMG 517 (Standard)659730-32-2TRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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