Amthamine dihydrobromide

Name: Amthamine dihydrobromide
Brand: MedChemExpress
SKU: HY-101063
Rating: 4.5 (1 reviews)

Cat. No.: HY-101063 Purity: 99.64%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .

For research use only. We do not sell to patients.

Amthamine dihydrobromide Chemical Structure

CAS No. : 142457-00-9

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Amthamine dihydrobromide:

Amthamine Get quote

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H₁ Receptor H₂ Receptor H₃ Receptor H₄ Receptor Histamine Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

319.07

Formula

C₆H₁₃Br₂N₃S

CAS No.

142457-00-9

Appearance

Solid

Color

White to yellow

SMILES

NCCC1=C(C)N=C(N)S1.Br.Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (313.41 mM; Need ultrasonic)

DMSO : 83.33 mg/mL (261.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1341 mL	15.6707 mL	31.3415 mL
5 mM	0.6268 mL	3.1341 mL	6.2683 mL
10 mM	0.3134 mL	1.5671 mL	3.1341 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.64%

Select Batch:

Data Sheet (268 KB) SDS (393 KB)

COA (247 KB) HNMR (265 KB) LCMS (83 KB)

Handling Instructions (2659 KB)

References

[1]. Trivendra Tripathi, et al. Hepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R-(-)-α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental Model. American Medical Journal. 2010, 1 (1): 1-7.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.1341 mL	15.6707 mL	31.3415 mL	78.3537 mL
	5 mM	0.6268 mL	3.1341 mL	6.2683 mL	15.6707 mL
	10 mM	0.3134 mL	1.5671 mL	3.1341 mL	7.8354 mL
	15 mM	0.2089 mL	1.0447 mL	2.0894 mL	5.2236 mL
	20 mM	0.1567 mL	0.7835 mL	1.5671 mL	3.9177 mL
	25 mM	0.1254 mL	0.6268 mL	1.2537 mL	3.1341 mL
	30 mM	0.1045 mL	0.5224 mL	1.0447 mL	2.6118 mL
	40 mM	0.0784 mL	0.3918 mL	0.7835 mL	1.9588 mL
	50 mM	0.0627 mL	0.3134 mL	0.6268 mL	1.5671 mL
	60 mM	0.0522 mL	0.2612 mL	0.5224 mL	1.3059 mL
	80 mM	0.0392 mL	0.1959 mL	0.3918 mL	0.9794 mL
	100 mM	0.0313 mL	0.1567 mL	0.3134 mL	0.7835 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.