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  4. Amthamine dihydrobromide

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .

For research use only. We do not sell to patients.

Amthamine dihydrobromide Chemical Structure

Amthamine dihydrobromide Chemical Structure

CAS No. : 142457-00-9

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5 mg USD 80 In-stock
10 mg USD 120 In-stock
25 mg USD 240 In-stock
50 mg USD 390 In-stock
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200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Amthamine dihydrobromide:

Amthamine dihydrobromide Related Antibodies

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Description

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

Molecular Weight

319.06

Formula

C6H13Br2N3S
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

NCCC1=C(C)N=C(N)S1.Br.Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (313.42 mM; Need ultrasonic)

DMSO : 83.33 mg/mL (261.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1342 mL 15.6710 mL 31.3421 mL
5 mM 0.6268 mL 3.1342 mL 6.2684 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.64%

COA (247 KB) HNMR (265 KB) LCMS (83 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.1342 mL 15.6710 mL 31.3421 mL 78.3552 mL
5 mM 0.6268 mL 3.1342 mL 6.2684 mL 15.6710 mL
10 mM 0.3134 mL 1.5671 mL 3.1342 mL 7.8355 mL
15 mM 0.2089 mL 1.0447 mL 2.0895 mL 5.2237 mL
20 mM 0.1567 mL 0.7836 mL 1.5671 mL 3.9178 mL
25 mM 0.1254 mL 0.6268 mL 1.2537 mL 3.1342 mL
30 mM 0.1045 mL 0.5224 mL 1.0447 mL 2.6118 mL
40 mM 0.0784 mL 0.3918 mL 0.7836 mL 1.9589 mL
50 mM 0.0627 mL 0.3134 mL 0.6268 mL 1.5671 mL
60 mM 0.0522 mL 0.2612 mL 0.5224 mL 1.3059 mL
80 mM 0.0392 mL 0.1959 mL 0.3918 mL 0.9794 mL
100 mM 0.0313 mL 0.1567 mL 0.3134 mL 0.7836 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Amthamine dihydrobromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amthamine dihydrobromide142457-00-9Othershistaminehistamine receptors-agonistsliver histopathologyhepatotoxicitypolypoidykupffer cellsInhibitorinhibitorinhibit

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