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AMXT1501 is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.

For research use only. We do not sell to patients.

AMXT-1501 Chemical Structure

AMXT-1501 Chemical Structure

CAS No. : 441022-64-6

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5 mg USD 550 In-stock
10 mg USD 850 In-stock
25 mg USD 1850 In-stock
50 mg USD 2850 In-stock
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Based on 4 publication(s) in Google Scholar

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Description

AMXT1501 is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells[1].

IC50 & Target

Polyamine transport[1]
Molecular Weight

568.92

Formula

C32H68N6O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCC(NCCCC[C@@H](N)C(NCCCNCCCCNCCCN)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (175.77 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7577 mL 8.7886 mL 17.5772 mL
5 mM 0.3515 mL 1.7577 mL 3.5154 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7577 mL 8.7886 mL 17.5772 mL 43.9429 mL
5 mM 0.3515 mL 1.7577 mL 3.5154 mL 8.7886 mL
10 mM 0.1758 mL 0.8789 mL 1.7577 mL 4.3943 mL
15 mM 0.1172 mL 0.5859 mL 1.1718 mL 2.9295 mL
20 mM 0.0879 mL 0.4394 mL 0.8789 mL 2.1971 mL
25 mM 0.0703 mL 0.3515 mL 0.7031 mL 1.7577 mL
30 mM 0.0586 mL 0.2930 mL 0.5859 mL 1.4648 mL
40 mM 0.0439 mL 0.2197 mL 0.4394 mL 1.0986 mL
50 mM 0.0352 mL 0.1758 mL 0.3515 mL 0.8789 mL
60 mM 0.0293 mL 0.1465 mL 0.2930 mL 0.7324 mL
80 mM 0.0220 mL 0.1099 mL 0.2197 mL 0.5493 mL
100 mM 0.0176 mL 0.0879 mL 0.1758 mL 0.4394 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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AMXT-1501 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMXT-1501441022-64-6AMXT1501AMXT 1501OthersInhibitorinhibitorinhibit

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