HTR2C Antibody (YA3364)

HTR2C Antibody (YA3364) is a biotin-conjugated non-conjugated IgG antibody, targeting HTR2C, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). HTR2C Antibody (YA3364) can be used for WB experiment in human, mouse, rat background.

The related gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of The related gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby related generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of The related gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of The related gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

3358

Predicted band size: 52 kDa; Observed band size: 75 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P28335

WB: 1/500-1/1000

WB

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human 5HT2C Receptor