Insulin Receptor Antibody (YA1540)

Insulin Receptor Antibody (YA1540) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1540), targeting Insulin Receptor, with a predicted molecular weight of 156 kDa (observed band size: 95 kDa). Insulin Receptor Antibody (YA1540) can be used for WB, ICC/IF experiment in human, rat background.

The related gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to related generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to The receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in The related gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

3643

Predicted band size: 156 kDa; Observed band size: 95 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Rat

P06213

WB: 1/500-1/1000;IF: 1/50-1/200

WB, ICC/IF

Liquid

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Insulin Receptor