NXF1 Antibody (YA1468)

NXF1 Antibody (YA1468) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1468), targeting NXF1, with a predicted molecular weight of 70 kDa (observed band size: 70 kDa). NXF1 Antibody (YA1468) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

The related gene is one member of a family of nuclear RNA export factor related genes. Common domain features of The family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in The related gene family. The encoded protein of The related gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.

10482

Predicted band size: 70 kDa; Observed band size: 70 kDa

Affinity Purified

Non-conjugated

Unmodified

Tags & Cell Markers

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q9UBU9

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human NXF1