PCBP1 Antibody (YA2927)

PCBP1 Antibody (YA2927) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2927), targeting PCBP1, with a predicted molecular weight of 37 kDa (observed band size: 40 kDa). PCBP1 Antibody (YA2927) can be used for WB, IP experiment in human, mouse, rat background.

The intronless related gene is thought to have been related generated by retrotransposition of a fully processed PCBP-2 mRNA. The related gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire related genes. The protein encoded by The related gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. The encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

5093

Predicted band size: 37 kDa; Observed band size: 40 kDa

Affinity Purified

Non-conjugated

Unmodified

-

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q15365

WB: 1/500-1/1000;IP: 1/50

WB, IP

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human PCBP1