PCSK9 Antibody (YA1550)

PCSK9 Antibody (YA1550) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1550), targeting PCSK9, with a predicted molecular weight of 74 kDa (observed band size: 65/80 kDa). PCSK9 Antibody (YA1550) can be used for WB, IP experiment in human background.

The related gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in The related gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.

255738

Predicted band size: 74 kDa; Observed band size: 65,80 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q8NBP7

WB: 1/500-1/1000;IP: 1/20

WB, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human PCSK9