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  3. Polyclonal Antibodies
  4. Phospho-AMPK alpha 2 (Thr172) Antibody

Phospho-AMPK alpha 2 (Thr172) Antibody

Cat. No.: HY-P80791
COA User Guide for Antibodies

Phospho-AMPK alpha 2 (Thr172) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 62 kDa, targeting to Phospho-AMPK alpha 2 (Thr172). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-AMPK alpha 2 (Thr172) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 62 kDa, targeting to Phospho-AMPK alpha 2 (Thr172). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

Background

AMPK alpha 2: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

Tag

Free

Gene ID

5563

Synonyms
PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
Molecular Weight

Predicted band size: 62 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Neuroscience

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P54646

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide

Storage & Stability

Stored at -20°C. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Thr172 of Human AMPK alpha.The exact sequence is proprietary to MCE.

Documentation

Phospho-AMPK alpha 2 (Thr172) Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-AMPK alpha 2 (Thr172) Antibody
Cat. No.:
HY-P80791
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