PUM1 Antibody (YA1781)

PUM1 Antibody (YA1781) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1781), targeting PUM1, with a predicted molecular weight of 126 kDa (observed band size: 140 kDa). PUM1 Antibody (YA1781) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

The related gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryorelated genesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

9698

Predicted band size: 126 kDa; Observed band size: 140 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

Q14671

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Pumilio 1