Rat Anti-Mouse CD86 Antibody (FITC)

Cat. No.: HY-P83710m: FAQs
Data Sheet User Guide for Antibodies

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

For research use only. We do not sell to patients.

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Biological Activity
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Description	CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Gene ID	12524
Synonyms	T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1
Purity	Affinity
Conjugation	FITC
Modification	Unmodified
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Clonality	Monoclonal
Host	Rat
Reactivity	Mouse
SwissProt ID	P42082
Dilution Ratio	FC: 5μL per test for million cells or whole blood in 100 μL volume.
Application	FC
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% Proclin300, 1% BSA.
Storage & Stability	Stored at 2-8°C for 1 year, protect from light, do not freeze.
Shipping	Shipping with blue ice.
Isotype	IgG2a
Immunogen	A synthesized peptide derived from Mouse CD86.
Documentation	Data Sheet (231 KB) User Guide for Antibodies (1077 KB)

Rat Anti-Mouse CD86 Antibody (FITC) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rat Anti-Mouse CD86 Antibody (FITC)

Biological Activity

Technical Parameters

Properties

Documentation

Rat Anti-Mouse CD86 Antibody (FITC) Related Classifications

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