Wilms Tumor Protein Antibody (YA2277)

Wilms Tumor Protein Antibody (YA2277) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2277), targeting Wilms Tumor Protein, with a predicted molecular weight of 49 kDa (observed band size: 55 kDa). Wilms Tumor Protein Antibody (YA2277) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.

The related gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. The related gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that The process is tissue-restricted and developmentally regulated.

7490

Predicted band size: 49 kDa; Observed band size: 55 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Tags & Cell Markers

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

P19544

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100

WB, IHC-P, ICC/IF, FC

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Wilms Tumor Protein