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  4. Anticancer agent 242

Anticancer agent 242 (7) possesses anticancer activity in A2780 (IC50 = 0.24 μM, ovarian adenocarcinoma), A2780cis (IC50 = 0.45 μM, resistant derivative of A2780), CCD18Co (IC50 = 0.59 μM, non-malignant human fibroblasts), A549 (IC50 = 0.32 μM, lung carcinoma), HT29 (IC50 = 0.26 μM, colorectal adenocarcinoma), and MCF7 (IC50 = 0.55 μM, breast adenocarcinoma).

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Anticancer agent 242 Chemical Structure

Anticancer agent 242 Chemical Structure

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Description

Anticancer agent 242 (7) possesses anticancer activity in A2780 (IC50 = 0.24 μM, ovarian adenocarcinoma), A2780cis (IC50 = 0.45 μM, resistant derivative of A2780), CCD18Co (IC50 = 0.59 μM, non-malignant human fibroblasts), A549 (IC50 = 0.32 μM, lung carcinoma), HT29 (IC50 = 0.26 μM, colorectal adenocarcinoma), and MCF7 (IC50 = 0.55 μM, breast adenocarcinoma)[1].

Molecular Weight

1101.82

Formula

C59H72ClF3N6O5S2
SMILES

FC1=C(F)C(SCCC2=CC=C(C(N3CCN(C(C4=CC=CC=C4C5=C(C=C/6)C(OC7=C5C=CC(N(CC)CC)=C7)=CC6=[N+](CC)\CC)=O)CC3)=O)C=C2)=C(F)C(NC8CCCCCCCCCCC8)=C1S(=O)(N)=O.[Cl-]
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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Anticancer agent 242 Related Classifications

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Keywords:

Anticancer agent 242Anticancer agent242Anticancer agent-242Othersovarian adenocarcinomanon-malignant human fibroblastslung carcinomaHT29colorectal adenocarcinomaMCF7breast adenocarcinomaInhibitorinhibitorinhibit

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