2. Apoptosis
  3. Apoptosis Caspase Bcl-2 Family
  4. Anticancer agent 63

Anticancer agent 63 (compound 3h) shows active in reducing the viability of different cancer cell lines, including SW480, HeLa, A549 and MCF-7, with IC50 values at 24 h of 4.9, 11.5, 9.4, and 3.4 μM, respectively. Anticancer agent 63 induce apoptosis in MCF-7 cells via down-regulating the expression of Bcl-2 and up-regulating the expression of IL-2 and Caspase-3. Anticancer agent 63 also shows antioxidant activity.

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Anticancer agent 63 Chemical Structure

Anticancer agent 63 Chemical Structure

CAS No. : 2529657-32-5

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Anticancer agent 63 Related Antibodies

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Description

Anticancer agent 63 (compound 3h) shows active in reducing the viability of different cancer cell lines, including SW480, HeLa, A549 and MCF-7, with IC50 values at 24 h of 4.9, 11.5, 9.4, and 3.4 μM, respectively. Anticancer agent 63 induce apoptosis in MCF-7 cells via down-regulating the expression of Bcl-2 and up-regulating the expression of IL-2 and Caspase-3. Anticancer agent 63 also shows antioxidant activity[1].

IC50 & Target

Caspase-3

 

Bcl-2

 

Molecular Weight

394.33

Formula

C17H24F3NOSe
CAS No.
SMILES

CC(CC1=CC=C(C=C1)C(C(NCCC[Se]C(F)(F)F)=O)C)C
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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Anticancer agent 63 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 632529657-32-5Anticancer agent63Anticancer agent-63ApoptosisCaspaseBcl-2 FamilySW480HeLaA549MCF-7NSAIDs-SeCF3 derivativeNSAIDsSelenocyanatesTrifluoromethyl selenidesanticancerprostateoral carcinomaInhibitorinhibitorinhibit

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