1. GPCR/G Protein
  2. Platelet-activating Factor Receptor (PAFR)
  3. Antiflammin 2

Antiflammin 2 inhibits the synthesis of platelet-activating factor (PAF) with the IC50 of 100 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Antiflammin 2 Chemical Structure

Antiflammin 2 Chemical Structure

CAS No. : 118850-72-9

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5 mg USD 300 In-stock
10 mg USD 500 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Antiflammin 2 inhibits the synthesis of platelet-activating factor (PAF) with the IC50 of 100 nM[1].

Molecular Weight

1084.25

Formula

C46H77N13O15S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

His-Asp-Met-Asn-Lys-Val-Leu-Asp-Leu

Sequence Shortening

HDMNKVLDL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (92.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9223 mL 4.6115 mL 9.2230 mL
5 mM 0.1845 mL 0.9223 mL 1.8446 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9223 mL 4.6115 mL 9.2230 mL 23.0574 mL
5 mM 0.1845 mL 0.9223 mL 1.8446 mL 4.6115 mL
10 mM 0.0922 mL 0.4611 mL 0.9223 mL 2.3057 mL
15 mM 0.0615 mL 0.3074 mL 0.6149 mL 1.5372 mL
20 mM 0.0461 mL 0.2306 mL 0.4611 mL 1.1529 mL
25 mM 0.0369 mL 0.1845 mL 0.3689 mL 0.9223 mL
30 mM 0.0307 mL 0.1537 mL 0.3074 mL 0.7686 mL
40 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.5764 mL
50 mM 0.0184 mL 0.0922 mL 0.1845 mL 0.4611 mL
60 mM 0.0154 mL 0.0769 mL 0.1537 mL 0.3843 mL
80 mM 0.0115 mL 0.0576 mL 0.1153 mL 0.2882 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Antiflammin 2
Cat. No.:
HY-P2606
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