2. Anti-infection
  3. Fungal
  4. Antifungal agent 122

Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-M enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity.

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Antifungal agent 122 Chemical Structure

Antifungal agent 122 Chemical Structure

CAS No. : 3054212-80-2

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Description

Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-M enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity[1].

Molecular Weight

508.51

Formula

C28H24F4N4O
CAS No.
SMILES

FC1=CC=C([C@@]([C@H](N(C)CC2=CC=C(C#CC3=CC=C(F)C=C3F)C=C2)C)(O)CN4N=CN=C4)C(F)=C1
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Room temperature in continental US; may vary elsewhere.
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Antifungal agent 122 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 1223054212-80-2Antifungal agent122Antifungal agent-122FungalH460 cellsOVCAR3 cellscytotoxicityfungal biofilmphase transitionInhibitorinhibitorinhibit

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