2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Apoptosis Reactive Oxygen Species
  4. Antiproliferative agent-7

Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis.

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Antiproliferative agent-7 Chemical Structure

Antiproliferative agent-7 Chemical Structure

CAS No. : 2497687-47-3

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Antiproliferative agent-7 Related Antibodies

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Description

Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis[1].

IC50 & Target

IC50: 3.5 μM (MCF-7), 15.54 μM (MDA-MB-231), 30.43 μM (HCT-116), 34.8 μM (FR-2)[1]
Molecular Weight

440.58

Formula

C28H32N4O
CAS No.
SMILES

CCN(CC)CCCOC1=CC=C(C2=C(C3=CC=CC=C3)N=NN2CC4=CC=CC=C4)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antiproliferative agent-7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiproliferative agent-72497687-47-3Antiproliferative agent7Antiproliferative agent 7ApoptosisReactive Oxygen SpeciesAntiproliferativeMCF-7MDA-MB-231HCT-116FR-2Inhibitorinhibitorinhibit

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