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  4. APC 366 TFA

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases.

For research use only. We do not sell to patients.

APC 366 TFA Chemical Structure

APC 366 TFA Chemical Structure

CAS No. : 2421110-28-1

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APC 366 TFA Related Antibodies

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Description

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

IC50 & Target

mast cell tryptase[1]
In Vivo

APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male BALB/c mice (18–25 g)[1]
Dosage: 5 mg/kg/0.1 ml
Administration: S.c.
Result: Reduced the eosinophil recruitment induced by PAR-2 activating peptide.
Molecular Weight

554.52

Formula

C24H29F3N6O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C(F)(F)F)=O.OC1=C(C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N)=O)=O)=O)C=CC3=C1C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Purity: ≥99.0%

COA (246 KB)

Handling Instructions (2659 KB)
References
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APC 366 TFA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

APC 3662421110-28-1APC366APC-366OthersirreversiblemasttryptaseallergiceosinophilrecruitmentPAR-2Inhibitorinhibitorinhibit

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APC 366 TFA
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HY-105999B
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