Apelin-36(human) TFA

Cat. No.: HY-P1064A Purity: 98.11%: FAQs
Data Sheet SDS COA Handling Instructions

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Apelin-36(human) TFA is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC₅₀ of 20 nM. Apelin-36(human) TFA shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC5₅₀=8.61). Apelin-36(human) TFA has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Apelin-36(human) TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 370	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Apelin-36(human) TFA:

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HIV HIV-1 HIV-2

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[3]

HIV-1

HIV-2

Molecular Weight

4309.85

Formula

C₁₈₆H₂₉₈F₃N₆₉O₄₅S

Appearance

Solid

Color

White to off-white

Sequence

Leu-Val-Gln-Pro-Arg-Gly-Ser-Arg-Asn-Gly-Pro-Gly-Pro-Trp-Gln-Gly-Gly-Arg-Arg-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Sequence Shortening

LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Purity & Documentation

Purity: 98.11%

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Data Sheet (261 KB) SDS (251 KB)

COA (243 KB) RP-HPLC (113 KB) MS (222 KB) Elemental Analysis Report (100 KB)

Handling Instructions (2659 KB)

References

[1]. Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998;251(2):471-476. [Content Brief]

[2]. Medhurst AD, Jennings CA, Robbins MJ, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem. 2003;84(5):1162-1172. [Content Brief]

[3]. Zou MX, Liu HY, Haraguchi Y, Soda Y, Tatemoto K, Hoshino H. Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett. 2000;473(1):15-18. [Content Brief]