2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation GPCR/G Protein
  3. Apoptosis Reactive Oxygen Species Protease Activated Receptor (PAR) Bcl-2 Family
  4. Apoptosis inducer 28

Apoptosis Inducer 28 (Compound X1) is an apoptosis-inducing agent with anticancer activity in vitro. Apoptosis Inducer 28 can arrest the cell cycle at the G1 phase, promote cell death, and induce apoptosis by disrupting mitochondrial membrane potential. Apoptosis inducer 28 can also decrease the production of reactive oxygen species, downregulate the gene expression of BAX, Bcl-xL, and Bcl-2, while upregulating the gene expression of PAR-4.

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Apoptosis inducer 28 Chemical Structure

Apoptosis inducer 28 Chemical Structure

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Apoptosis inducer 28 Related Antibodies

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Description

Apoptosis Inducer 28 (Compound X1) is an apoptosis-inducing agent with anticancer activity in vitro. Apoptosis Inducer 28 can arrest the cell cycle at the G1 phase, promote cell death, and induce apoptosis by disrupting mitochondrial membrane potential. Apoptosis inducer 28 can also decrease the production of reactive oxygen species, downregulate the gene expression of BAX, Bcl-xL, and Bcl-2, while upregulating the gene expression of PAR-4[1].

Molecular Weight

573.45

Formula

C26H22Cl2N4O5S
SMILES

O=C(NC1=CC=C(/N=C2C(NC3=C\2C=C(S(=O)(N4CCCCC4)=O)C=C3)=O)C=C1Cl)C5=CC(Cl)=CC=C5O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Apoptosis inducer 28 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 28Apoptosis inducer28Apoptosis inducer-28ApoptosisReactive Oxygen SpeciesProtease Activated Receptor (PAR)Bcl-2 FamilyThrombin receptorsMCF-7HCT-116HEPG-2VEROanticancer activityInhibitorinhibitorinhibit

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