1. Metabolic Enzyme/Protease
  2. FABP
  3. ART26.12

ART26.12 is an orally active and selective FABP5 inhibitor. ART26.12 has a high oral bioavailability in rats and dogs.

For research use only. We do not sell to patients.

ART26.12 Chemical Structure

ART26.12 Chemical Structure

CAS No. : 2766800-24-0

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5 mg USD 875 In-stock
10 mg USD 1400 In-stock
25 mg USD 2500 In-stock
50 mg USD 3500 In-stock
100 mg USD 4900 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

ART26.12 is an orally active and selective FABP5 inhibitor. ART26.12 has a high oral bioavailability in rats and dogs[1].

Molecular Weight

472.53

Formula

C29H28O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1[C@H](C2=C(C=CC=C2)OC)[C@@H]([C@H]1C3=C(C=CC=C3)OC)C(O)=O)OC4CC5=CC=CC=C5C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (264.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1163 mL 10.5813 mL 21.1627 mL
5 mM 0.4233 mL 2.1163 mL 4.2325 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1163 mL 10.5813 mL 21.1627 mL 52.9067 mL
5 mM 0.4233 mL 2.1163 mL 4.2325 mL 10.5813 mL
10 mM 0.2116 mL 1.0581 mL 2.1163 mL 5.2907 mL
15 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5271 mL
20 mM 0.1058 mL 0.5291 mL 1.0581 mL 2.6453 mL
25 mM 0.0847 mL 0.4233 mL 0.8465 mL 2.1163 mL
30 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7636 mL
40 mM 0.0529 mL 0.2645 mL 0.5291 mL 1.3227 mL
50 mM 0.0423 mL 0.2116 mL 0.4233 mL 1.0581 mL
60 mM 0.0353 mL 0.1764 mL 0.3527 mL 0.8818 mL
80 mM 0.0265 mL 0.1323 mL 0.2645 mL 0.6613 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.5291 mL
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ART26.12 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ART26.12
Cat. No.:
HY-159115
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