2. Stem Cell/Wnt
  3. β-catenin Wnt
  4. aStAx-35R TFA

aStAx-35R TFA, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R TFA inhibits competitively the binding of β-catenin to TCF4. aStAx-35R TFA selectively induces growth inhibition of Wnt-dependent cancer cells.

For research use only. We do not sell to patients.

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aStAx-35R TFA Chemical Structure

aStAx-35R TFA Chemical Structure

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1 mg USD 155 In-stock
5 mg USD 385 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of aStAx-35R TFA:

aStAx-35R TFA Related Antibodies

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Description

aStAx-35R TFA, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R TFA inhibits competitively the binding of β-catenin to TCF4. aStAx-35R TFA selectively induces growth inhibition of Wnt-dependent cancer cells[1].

Molecular Weight

2392.86 (free base)

Formula

C111H178N40O20.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence Shortening

Ac-RRWPR-S5-ILD-S5-HVRRVWR-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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aStAx-35R TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

aStAx-35Rβ-cateninWntBeta cateninWnt signalingcancerInhibitorinhibitorinhibit

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