2. Stem Cell/Wnt
  3. β-catenin Wnt
  4. aStAx-35R

aStAx-35R, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R inhibits competitively the binding of β-catenin to TCF4. aStAx-35R selectively induces growth inhibition of Wnt-dependent cancer cells.

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aStAx-35R Chemical Structure

aStAx-35R Chemical Structure

CAS No. : 1418863-17-8

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aStAx-35R Related Antibodies

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Description

aStAx-35R, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R inhibits competitively the binding of β-catenin to TCF4. aStAx-35R selectively induces growth inhibition of Wnt-dependent cancer cells[1].

Molecular Weight

2392.86

Formula

C111H178N40O20
CAS No.
Sequence Shortening

Ac-RRWPR-S5-ILD-S5-HVRRVWR-NH2
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Purity & Documentation
References
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aStAx-35R Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

aStAx-35R1418863-17-8β-cateninWntBeta cateninWnt signalingcancerInhibitorinhibitorinhibit

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