2. Anti-infection
  3. Bacterial
  4. Atractylodinol

Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates.

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Atractylodinol Chemical Structure

Atractylodinol Chemical Structure

CAS No. : 61642-89-5

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Atractylodinol Related Antibodies

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Description

Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates[1][2].

Cellular Effect
Cell Line Type Value Description References
BMDM IC50
0.64 μM
Compound: 32
Anti-osteoclastogensis activity C57BL/6 mouse bone marrow macrophages assessed as inhibition of RANKL-induced osteoclastogenesis and measured after 5 days in presence of M-CSF by TRAP staining based assay
Anti-osteoclastogensis activity C57BL/6 mouse bone marrow macrophages assessed as inhibition of RANKL-induced osteoclastogenesis and measured after 5 days in presence of M-CSF by TRAP staining based assay
[PMID: 35324175]
Molecular Weight

198.22

Formula

C13H10O2
CAS No.
SMILES

OC/C=C/C#CC#C/C=C/C1=CC=CO1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Atractylodinol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atractylodinol61642-89-5BacterialPRRSV inhibitorantimicrobialvimentinanti-pulmonary fibrosisInhibitorinhibitorinhibit

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