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  4. Aucuparin

Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (BLM)-induced lung fibrosis mouse model. Anti-inflammatory activity.

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Aucuparin Chemical Structure

Aucuparin Chemical Structure

CAS No. : 3687-28-3

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Based on 1 publication(s) in Google Scholar

Aucuparin Related Antibodies

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Description

Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (BLM)-induced lung fibrosis mouse model. Anti-inflammatory activity[1][2].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 8
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
[PMID: 19813743]
BV-2 IC50
50.15 μM
Compound: 3
Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
[PMID: 26706168]
HCT-15 IC50
> 10 μM
Compound: 8
Cytotoxicity against human HCT15 cells by SRB assay
Cytotoxicity against human HCT15 cells by SRB assay
[PMID: 19813743]
SK-MEL-2 IC50
> 10 μM
Compound: 8
Cytotoxicity against human SK-MEL-2 cells by SRB assay
Cytotoxicity against human SK-MEL-2 cells by SRB assay
[PMID: 19813743]
SK-OV-3 IC50
> 10 μM
Compound: 8
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
[PMID: 19813743]
Molecular Weight

230.26

Formula

C14H14O3
CAS No.
SMILES

OC1=C(OC)C=C(C=C1OC)C2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aucuparin Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aucuparin3687-28-3Otherspulmonary fibrosisinflammationInhibitorinhibitorinhibit

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Product Name:
Aucuparin
Cat. No.:
HY-137992
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